Advanced Solutions
for Advanced Pathology
Varicella Zoster Virus (SG1-1, SG1-SG4, NCP-1 & IE-62)
Mouse Cocktail Antibody
Cat. No. Description
Volume
45269 IMPATH Varicella Zoster Virus RTU M (Monocl CKT)
50 Tests
44407 Varicella-zoster virus RTU M (MONOCLONAL CKT)
7 ml Ready To Use
44833 Varicella-zoster virus 0,1 M (MONOCLONAL CKT)
100 µl liquid Concentrated
44834 Varicella-zoster virus 1 M (MONOCLONAL CKT)
1 ml liquid Concentrated
Product Specifications
Designation
IVD
Reactivity
Paraffin
Visualization
Cytoplasmic, Membranous
Control
Varicella Zoster Virus infected tissue
Stability
Up to 36 mo. at 2-8°C
Isotype
Mixed
Manual Protocol*
• Pretreatment: Heat Induced Epitope
Retrieval (HIER)
• Primary Antibody Incubation Time:
10-30min @ 25-37°C
• 2-step polymer detection
*Please refer to product insert for complete protocol.
ImPath Protocol*
• Dewax: Dewax Solution 2 (DS2)
• Pretreatment: Retrieval Solution pH 9.0
(TR1) 32min @ 98-103°C
• Primary Antibody Incubation Time:
10-90min @ 25-37°C
• HRP Polymer (Universal) or AP Polymer
(Universal) for 12 min
*Please refer to product insert for complete protocol.
Product Description
Varicella zoster virus (VZV), a member of the human herpes virus family, causes two distinct clinical manifestations: Chickenpox and shingles.
Primary VZV infection results in chickenpox (varicella), which may rarely result in complications including encephalitis or pneumonia. Even when
clinical symptoms of chickenpox have resolved, VZV remains dormant in the nervous system (virus latency) in the trigeminal and dorsal root
ganglia. In about 10%-20% of cases, VZV reactivates later in life producing a disease known as herpes zoster or shingles. Serious complications
of shingles include postherpetic neuralgia, zoster multiplex, myelitis, herpes ophthalmicus, or zoster sine herpete.
VZV is closely related to the herpes simplex virus (HSV). Affected skin shares so many histological similarities that distinguishing between them
may be difficult. Anti-VZV is directed against the VZV virus.
Reference
1. Kleinschmidt D, et al. J Neurol Sci. 1998 Aug 14; 159(2):213-8.
2. Kaye SB, et al. Br J Ophthalmol. 2000 Jun; 84(6):563-71.
3. A.F. Nikkels, et al. Virchows Archiv. 1993; 422:121-126.
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