Antibodies for
Immunohistochemistry
Prolactin (Polyclonal)
Rabbit Polyclonal Antibody
Cat. No. Description
Volume
45328 IMPATH Prolactin RTU R (Poly)
50 Tests
44377 Prolactin RTU R (Poly)
7 ml Ready To Use
44773 Prolactin 0,1 R (Poly)
100 µl liquid Concentrated
44774 Prolactin 1 R (Poly)
1 ml liquid Concentrated
Product Specifications
Designation
IVD
Reactivity
Paraffin
Visualization
Cytoplasmic
Control
Pituitary
Stability
Up to 36 mo. at 2-8°C
Manual Protocol*
• Pretreatment: Heat Induced Epitope
Retrieval (HIER)
• Primary Antibody Incubation Time:
10-30min @ 25-37°C
• 2-step polymer detection
*Please refer to product insert for complete protocol.
ImPath Protocol*
• Dewax: Dewax Solution 2 (DS2)
• Pretreatment: Retrieval Solution pH 9.0
(TR1) 32min @ 98-103°C
• Primary Antibody Incubation Time:
10-90min @ 25-37°C
• HRP Polymer (Universal) or AP Polymer
(Universal) for 12 min
*Please refer to product insert for complete protocol.
Product Description
Prolactin (PRL) is a single-chain polypeptide of 226 amino acids with a molecular weight of about 24 kD. Prolactin plays a role in multiple
processes including cell growth, reproduction, and immune function. The pituitary hormone PRL is involved in tumorigenesis in rodents and
humans. PRL promotes proliferation, survival, and migration of cancer cells acting via the PRL receptor.
Anti-prolactin is a useful marker in classification of pituitary tumors and the study of pituitary disease. It reacts with prolactin-producing cells.
Such prolactin-producing cells can also be found in prostate epithelium.
Pituitary Panel
Prolactin
ACTH
FSH
GH
LH
TSH
Pituitary
+
+
+
+
+
+
Reference
1. Asa SL, et al. Arch Pathol Lab Med. 1982; 106:360.
2. Duello TM, et al. Amer J Anat. 1980; 158:463.
3. Minniti G, et al. Surg Neurol. 2002 Feb; 57(2):99-103.
4. Popadic A, et al. Surg Neurol. 1999 Jan; 51(1):47-54.
5. Nevalainen MT, et al. J Clin Invest. 1997 Feb 15; 99(4):618-2.
208
