Antibodies for
Immunohistochemistry
CD79a (JCB117)
Mouse Monoclonal Antibody
Cat. No. Description
Volume
45190 IMPATH CD79a RTU M (JCB117)
50 Tests
44253 CD79a RTU M (JCB117)
7 ml Ready To Use
44527 CD79a 0,1 M (JCB117)
100 µl liquid Concentrated
44528 CD79a 1 M (JCB117)
1 ml liquid Concentrated
Product Specifications
Designation
IVD
Reactivity
Paraffin
Visualization
Membranous
Control
Tonsil
Stability
Up to 36 mo. at 2-8°C
Isotype
IgG
1
/k
Manual Protocol*
• Pretreatment: Heat Induced Epitope
Retrieval (HIER)
• Primary Antibody Incubation Time:
10-30min @ 25-37°C
• 2-step polymer detection
*Please refer to product insert for complete protocol.
ImPath Protocol*
• Dewax: Dewax Solution 2 (DS2)
• Pretreatment: Retrieval Solution pH 9.0
(TR1) 32min @ 98-103°C
• Primary Antibody Incubation Time:
10-90min @ 25-37°C
• HRP Polymer (Universal) or AP Polymer
(Universal) for 12 min
*Please refer to product insert for complete protocol.
Product Description
Anti-CD79a is a B-cell marker that is generally used to complement anti-CD20 especially for mature B-cell lymphomas after treatment with
Rituximab (anti-CD20). This antibody will stain many of the same lymphomas as anti-CD20, but also is more likely to stain B-lymphoblastic
lymphoma/leukemia than is anti-CD20. Anti-CD79a also stains more cases of plasma cell myeloma and occasionally some types of endothelial
cells as well.
B-cell Lymphomas
CD79a PAX-5 MUM1 BCL2
BCL6
p27
CD10
CD23 Cyclin D1 TRAcP
Follicular
+
+
-
+
+
+
+
-
-
-
CLL/SLL
+
+
+
+
-
+
-
+
-
-
Mantle Cell
+
+
-
+
-
+
-
-
+
-
Marginal Zone BCL
+
+
+
+
-
+
-
-
-
+/-
Lymphoplasmacytic
+
+
+
+
-
+
-
-
-
-
Diffuse Large Cell
Lymphoma
+
+
+
+
+
-
-
-
-
-
Burkitt Lymphoma
+
+
-
-
+
-
+
-
-
-
Hairy Cell Leukemia
+
+
+
-
-
-
-
+(weak)/-
+
Plasma Cells
CD79a
CD138
EMA
MUM1
CD56 Cyclin D1 CD43
CD20
CD19
Plasma Cell Neoplasm
+
+
+
+
+
-/+
-
-/+
-
Reference
1. Kurtin PJ, et al. Am J Clin Pathol. 1999 Sep; 112(3):319-29.
2. Blakolmer K, et al. Mod Pathol. 2000 Jul; 13(70:766-72.
3. Yao X, et al. Mod Pathol. 2001 Feb; 14(2):105-10.
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