Advanced Solutions
for Advanced Pathology
MART-1 (Melan A) (A103)
Mouse Monoclonal Antibody
Cat. No. Description
Volume
45152 IMPATH MART-1 (Melan A) RTU M (A103)
50 Tests
44332 MART-1 (Melan A) RTU M (A103)
7 ml Ready To Use
44686 MART-1 (Melan A) 0,1 M (A103)
100 µl liquid Concentrated
44687 MART-1 (Melan A) 1 M (A103)
1 ml liquid Concentrated
Product Specifications
Designation
IVD
Reactivity
Paraffin
Visualization
Cytoplasmic
Control
Melanoma, Skin
Stability
Up to 36 mo. at 2-8°C
Isotype
IgG
1
Manual Protocol*
• Pretreatment: Heat Induced Epitope
Retrieval (HIER)
• Primary Antibody Incubation Time:
10-30min @ 25-37°C
• 2-step polymer detection
*Please refer to product insert for complete protocol.
ImPath Protocol*
• Dewax: Dewax Solution 2 (DS2)
• Pretreatment: Retrieval Solution pH 9.0
(TR1) 32min @ 98-103°C
• Primary Antibody Incubation Time:
10-90min @ 25-37°C
• HRP Polymer (Universal) or AP Polymer
(Universal) for 12 min
*Please refer to product insert for complete protocol.
Product Description
MART-1 (also known as Melan A) is a melanocyte differentiation antigen. It is present in melanocytes of normal skin, retina, nevi, and in more than
85% of melanomas. This antibody is very useful in establishing the diagnosis of metastatic melanomas.
Adrenal Tumors
MART-1
Inhibin
Calretinin
Synaptophysin Chromogranin A
CD56
Pheochromocytoma
-
-
-
+
+
+
Adrenal Carcinoma
+
+
+
-/+
-
+
Adrenal Adenoma
+
+
+
-/+
-
+
Melanotic Lesions
MART-1
S-100
SOX-10
HMB-45 Tyrosinase
MiTF
CD63
Factor XIIIa
Adult Melanocytes
+
+
+
-
+
+
+
-
Junctional Nevus
+
+
+
+
+
+
-
-
Interdermal Nevus
+
+
+
-
+
+
-
-
Primary Melanoma
+
+
+
+
+
+
+
-
Metastatic Melanoma
+
+
+
+
+
+
+
-
Spindle Cell Melanoma
+
+
+
+
+
+
+
-
Angiomyolipoma
+
+
+
+
-
+
+
-
Adrenal Cortical
+
+
-
-
-
-
-
Intranodal Nevus Cells
+
+
+
-
+
+
-
-
Dermatofibroma
-
-
-
-
-
-
-
+
PEComa
MART-1 HMB-45 CD63
S-100 Tyrosinase SM Actin Calponin Caldesmon Desmin CD68
Angiomyolipoma
+
+
+
-
-
+
+
+
-
+
Lymphangiomyomatosis
+
+
+
-
-
+
+
+
-
-
Extrapulmonary Clear Cell
Tumor
+
+
+
+
-
+
-
-
-
-
Primary Cutaneous
PEComa
+
+
+
-
-
-
-
-
-
+/-
Pulmonary Clear Cell Sugar
Tumor
+
+
+
+/-
-
-
-
-
-
+/-
Reference
1. Kageshita T, et al. J Immunother. 1997 Nov; 20(6):460-5.
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