Antibodies for
Immunohistochemistry
Myeloperoxidase (Polyclonal)
Rabbit Polyclonal Antibody
Cat. No. Description
Volume
45237 IMPATH Myeloperoxidase RTU R (Poly)
50 Tests
44347 Myeloperoxidase RTU R (Poly)
7 ml Ready To Use
44714 Myeloperoxidase 0,1 R (Poly)
100 µl liquid Concentrated
44715 Myeloperoxidase 1 R (Poly)
1 ml liquid Concentrated
Product Specifications
Designation
IVD
Reactivity
Paraffin
Visualization
Cytoplasmic
Control
Bone Marrow
Stability
Up to 36 mo. at 2-8°C
Manual Protocol*
• Pretreatment: Heat Induced Epitope
Retrieval (HIER)
• Primary Antibody Incubation Time:
10-30min @ 25-37°C
• 2-step polymer detection
*Please refer to product insert for complete protocol.
ImPath Protocol*
• Dewax: Dewax Solution 2 (DS2)
• Pretreatment: Retrieval Solution pH 9.0
(TR1) 32min @ 98-103°C
• Primary Antibody Incubation Time:
10-90min @ 25-37°C
• HRP Polymer (Universal) or AP Polymer
(Universal) for 12 min
*Please refer to product insert for complete protocol.
Product Description
Anti-myeloperoxidase detects granulocytes and monocytes in blood and precursors of granulocytes in the bone marrow. This antibody can
detect myeloid cell populations of the bone marrow as well as in other sites.
Acute Myeloid Leukemia
MPO CD68 Factor VIII
CD61 Lysozyme BOB.1
Oct-2
Glyco-
phorin A CD34
Acute Myeloid, M0
-
-
-
-
+
-
-
-
+
Acute Myeloid, M1&2
+
+
-
-
+
-
+
Promyelocytic, M3
+
-
-
-
-
+
+
-
-
Myelomonocytic, M4
+
+
-
-
+
-
+
-
+
Monoblastic, M5
+
+
-
-
+
-
+
-
-/+
Acute Erythroid, M6
+
-
-
-
-
-
+
-/+
Megakaryoblastic, M7
-
-
+
+
+/-
-
-
-
Histiocytic Neoplasms
MPO CD45
CD4
CD68 Lysozyme CD163 Factor XIIIa CD20
CD3
Histiocytic Neoplasms
+
+
+
+
+
+
+
-
-
Reference
1. Pinkus GS, Pinkus JL. Mod Pathol. 1991 Nov; 4(6):733-41.
2. Hudock J, et al. Am J Clin Pathol. 1994 Jul; 102(1):55-60.
3. Hamoudi WH, et al. Arch Pathol Lab Med. 2000 Feb; 124(2):315-8.
4. Arber DA, et al. Am J Clin Pathol. 1996 Oct; 106(4):462-8.
5. Chang CC, et al. Am J Clin Pathol. 2000 Nov; 114(5):807-11.
6. Kaleem Z, White G. Am J Clin Pathol. 2001 Jun; 115(6):876-84.
7. Audouin J, et al. Int J Surg Pathol. 2003 Oct; 11(4):271-82.
8. Kojima M, et al. APMIS. 2003 Dec; 111(12):1133-6.
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