Advanced Solutions
for Advanced Pathology
Herpes Simplex Virus I (Polyclonal)
Rabbit Polyclonal Antibody
Cat. No. Description
Volume
45214 IMPATH Herpes Simplex Virus I RTU R (PolY) 50 Tests
44308 Herpes simplex virus I RTU R (Poly)
7 ml Ready To Use
44638 Herpes simplex virus I 0,1 R (Poly)
100 µl liquid Concentrated
44639 Herpes simplex virus I 1 R (Poly)
1 ml liquid Concentrated
Product Specifications
Designation
IVD
Reactivity
Paraffin
Visualization
Cytoplasmic, Nuclear
Control
HSV I infected tissue
Stability
Up to 36 mo. at 2-8°C
Manual Protocol*
• Pretreatment: Heat Induced Epitope
Retrieval (HIER)
• Primary Antibody Incubation Time:
10-30min @ 25-37°C
• 2-step polymer detection
*Please refer to product insert for complete protocol.
ImPath Protocol*
• Dewax: Dewax Solution 2 (DS2)
• Pretreatment: Retrieval Solution pH 9.0
(TR1) 32min @ 98-103°C
• Primary Antibody Incubation Time:
10-90min @ 25-37°C
• HRP Polymer (Universal) or AP Polymer
(Universal) for 12 min
*Please refer to product insert for complete protocol.
Product Description
Herpes simplex virus is quite ubiquitous and is variable in its presentation in human disease. Type I usually infects the non-genital mucosal
surfaces. It may affect the skin or internal organs (typically brain, lung, liver, adrenal gland, or GI tract) of immunocompromised individuals. This
polyclonal antibody reacts with Type I Herpes viruses. There may be cross-reactivity with varicella zoster virus at higher concentrations. Cross-
reactivity with CMV or Epstein-Barr virus is not seen with this antibody.
Reference
1. Adams RL, et al. J Pathol. 1984; 143:241-7.
2. Silverberg SG, et al. Principles and Practice of Surgical Pathology and CytoPathology, 3rd edition. 1997; 214-217.
3. Vago L, et al. Acta Neuropathol (Berl). 1996 Oct; 92(4):404-8.
4. Nikkels AF, et al. J C lin Pathol. 1996 Mar; 49(3):243-8.
5. Shintaku M, et al. Arch Pathol Lab Med. 2003 Feb; 127(2):231-4.
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