ImPath - page 135

Advanced Solutions
for Advanced Pathology
Hepatitis B Virus Core Antigen (Polyclonal)
Rabbit Polyclonal Antibody
Cat. No. Description
Volume
45212 IMPATH Hepatitis B Virus Core RTU R (Poly) RUO 50 Tests
44304 Hepatitis B Virus Core Antigen RTU R (Poly) RUO 7 ml Ready To Use
44630 Hepatitis B Virus Core Antigen 0,1 R (Poly) RUO 100 µl liquid Concentrated
44631 Hepatitis B Virus Core Antigen 1 R (Poly) RUO 1 ml liquid Concentrated
Product Specifications
Designation
IVD
Reactivity
Paraffin
Visualization
Nuclear
Control
Hepatitis B infected tissue
Stability
Up to 36 mo. at 2-8°C
Manual Protocol*
• Pretreatment: Heat Induced Epitope
Retrieval (HIER)
• Primary Antibody Incubation Time:
10-30min @ 25-37°C
• 2-step polymer detection
*Please refer to product insert for complete protocol.
ImPath Protocol*
• Dewax: Dewax Solution 2 (DS2)
• Pretreatment: Retrieval Solution pH 9.0
(TR1) 32min @ 98-103°C
• Primary Antibody Incubation Time:
10-90min @ 25-37°C
• HRP Polymer (Universal) or AP Polymer
(Universal) for 12 min
*Please refer to product insert for complete protocol.
Product Description
Anti-hepatitis B core antigen labels cell nuclei infected with hepatitis B virus, a common cause of hepatitis leading to cirrhosis. Hepatitis B is the
second most common cause of parenterally transmitted hepatitis.
Reference
1. Inohara H, et al. Cancer. 1999; 85:2475-84.
2. Herrmann ME, et al. Arch Pathol Lab Med. 2002; 126:710-713.
3. Papotti M, et al. European Journal of Endocrinology. 2002; 147:515-521.
4. Bartolazzi A, et al. Lancet. 2001; 357:1644-50.
5. Orlandi F, et al. Cancer Research. 1998 Jul 15; 58, 3015-3020.
6. Gasbarri A, et al. J Clin Oncol. 17:3494-3502.
7. Orlandi F, et al. Cancer Res. 1998 Jul 15; 58(14):3015-20.
8. Konstantinov KN, et al. Am J Pathol. 1996 Jan; 148(1):25-30.
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