Antibodies for
Immunohistochemistry
IgD (Polyclonal)
Rabbit Polyclonal Antibody
Cat. No. Description
Volume
45218 IMPATH IgD RTU R (Poly)
50 Tests
44316 IgD RTU R (Poly)
7 ml Ready To Use
44656 IgD 0,1 R (Poly)
100 µl liquid Concentrated
44657 IgD 1 R (Poly)
1 ml liquid Concentrated
Product Specifications
Designation
IVD
Reactivity
Paraffin
Visualization
Cytoplasmic
Control
Tonsil
Stability
Up to 36 mo. at 2-8°C
Manual Protocol*
• Pretreatment: Heat Induced Epitope
Retrieval (HIER)
• Primary Antibody Incubation Time:
10-30min @ 25-37°C
• 2-step polymer detection
*Please refer to product insert for complete protocol.
ImPath Protocol*
• Dewax: Dewax Solution 2 (DS2)
• Pretreatment: Retrieval Solution pH 9.0
(TR1) 32min @ 98-103°C
• Primary Antibody Incubation Time:
10-90min @ 25-37°C
• HRP Polymer (Universal) or AP Polymer
(Universal) for 12 min
*Please refer to product insert for complete protocol.
Product Description
Anti-IgD reacts with surface immunoglobulin D delta chains. This antibody is useful when identifying leukemias, plasmacytomas, and B-cell
lineage-derived lymphomas (in particular marginal zone lymphoma). Cytoplasmic staining is easily identified on paraffin tissue.
Immunoglobulin, Heavy and Light Chain
IgD
IgA
IgG
IgM
Kappa
Lambda
Secretory Meningioma
-
+
-
+
Cutaneous Lymphoma
-
-
-
-
+/-
-/+
Myeloma
-/+
+
+
-/+
+/-
-/+
Diffuse LBCL
-
-
+
+
+/-
-/+
Marginal Zone Lymphoma
-/+
-
-
+
+/-
-/+
SLL/CLL
+
-
-
+
+/-
-/+
B-cell Lymphomas
IgD CD79a BCL2
BCL6 MUM1 CD10
CD23 Cyclin D1 p27
Annexin
A1
Follicular
+
+
+
+
-
+
-
-
+
-
CLL/SLL
+
+
+
-
+
-
+
-
+
-
Mantle Cell
+
+
+
-
-
-
-
+
+
-
Marginal Zone BCL
-/+
+
+
-
+
-
-
-
+
-
Lymphoplasmacytic
-
+
+
-
+
-
-
-
+
-
Diffuse Large Cell
Lymphoma
-
+
+
+
+
-
-
-
-
Burkitt Lymphoma
-
+
-
+
-
+
-
-
-
Hairy Cell Leukemia
-
+
+
-
-
-
+(weak)/-
-
+
Reference
1. Campo E, et al. Am J Surg Pathol. 1999 Jan; 23(1):59-68.
2. Mori S, et al. Acta Pathol Jpn. 1986 Oct; 36(1):1429-40.
3. Oka K, et al. Acta Haematol. 1993; 90(2):84-9.
4. Bertero M, et al. J Am Acad Dermatol. 1994 Jan; 30(1):23-30.
5. Mollego M, et al, Isaacson PG. Am J Surg Pathol. 1997 Jul; 21(7):772-80.
6. Tang X, et al. Pathol Int. 1995 Jan; 45(1):34-44.
7. Gupta D, et al. Mod Pathol. 2000 Nov; 13(11):1161-6.
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