Antibodies for
Immunohistochemistry
Herpes Simplex Virus II (Polyclonal)
Rabbit Polyclonal Antibody
Cat. No. Description
Volume
45215 IMPATH Herpes Simplex Virus II RTU R (Poly) 50 Tests
44309 Herpes simplex virus II RTU R (Poly)
7 ml Ready To Use
44640 Herpes simplex virus II 0,1 R (Poly)
100 µl liquid Concentrated
44641 Herpes simplex virus II 1 R (Poly)
1 ml liquid Concentrated
Product Specifications
Designation
IVD
Reactivity
Paraffin
Visualization
Cytoplasmic, Nuclear
Control
HSV II infected tissue
Stability
Up to 36 mo. at 2-8°C
Manual Protocol*
• Pretreatment: Heat Induced Epitope
Retrieval (HIER)
• Primary Antibody Incubation Time:
10-30min @ 25-37°C
• 2-step polymer detection
*Please refer to product insert for complete protocol.
ImPath Protocol*
• Dewax: Dewax Solution 2 (DS2)
• Pretreatment: Retrieval Solution pH 9.0
(TR1) 32min @ 98-103°C
• Primary Antibody Incubation Time:
10-90min @ 25-37°C
• HRP Polymer (Universal) or AP Polymer
(Universal) for 12 min
*Please refer to product insert for complete protocol.
Product Description
Herpes simplex virus is quite ubiquitous and is quite variable in its presentation in human disease. Type II typically involves the genitalia. It
may affect the skin or internal organs (typically brain, lung, liver, adrenal gland, or GI tract) of immunocompromised individuals. This polyclonal
antibody reacts with Type II Herpes viruses. There may be cross-reactivity with varicella zoster virus at higher concentrations. Cross-reactivity
with CMV or Epstein-Barr virus is not seen with this antibody.
Reference
1. Adams RL, et al. J Pathol. 1984; 143:241-7.
2. Silverberg SG, et al. Principles and Practice of Surgical Pathology and CytoPathology, 3rd edition. 1997; 214-217.
3. Vago L, et al. Acta Neuropathol (Berl). 1996 Oct; 92(4):404-8.
4. Nikkels AF, et al. J C lin Pathol. 1996 Mar; 49(3):243-8.
5. Shintaku M, et al. Arch Pathol Lab Med. 2003 Feb; 127(2):231-4.
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